Mike Twardoski, a former professional player with four major league organizations, assumed the Emory head coach position prior to the 2000 season. Twardoski has guided the Eagles to six NCAA Division III World Series appearances, six NCAA regional championships, 11 NCAA tournament berths and 12 conference championships.

In 24 seasons at the helm of the Eagles, Twardoski has a career record of 652-320-1. He has guided the Eagles to nine seasons of 30 or more wins including a school-record 43 truimphs during the 2007 campaign.

Twardoski reached the 600 career wins milestone with the team's first win during the 2022 season, a year bookended with them going 11-2 down the stretch to capture a share of the UAA Championship for the first time in seven season. After guiding the program to its first conference title since 2015, Twardoski and his staff was honored by being named the UAA's Coaching Staff of the Year.

During the 2016 season, Twardoski became just the fourth coach in Emory history and only the 39th active Division III baseball coach to reach the 500 wins milestone as the Eagles defeated the University of Chicago 15-4 on March 26th. Twardoski was honored as D3Baseball.com and ABCA/Diamond All-South Region and UAA Coach of the Year accolades as the Eagles finished the season with a 34-12 overall record with a third straight appearance in the College World Series.

Twardoski's teams finished second at the Division III World Series in 2007 and 2014, fifth in 2003, sixth in 2015 and seventh in 2000 and 2016. His teams have compiled final national rankings of second (2007 and 2014), fifth (2003, 2015 and 2016), seventh (2000), ninth (2001 and 2004). During the regular season, Emory was ranked as high as No. 1 in the nation in 2001 by the ABCA and ascended to No. 1 in the D3Baseball.com rankings for the first in 2017.

Twardoski was honored as the regional Division III Coach of the Year in 2000 and 2016, and as the state Division III Coach of the Year by the Georgia Dugout Club in 2001, 2003 and 2004. In 2016, Twardoski and his assistants, Bobby Perez and Sean Kelly, were honored as the UAA Coaching Staff of the Year.

During his time with the team, Twardoski has overseen the development of nine all-Americans, two national gold glove winners, nine UAA Most Valuable Players, six UAA Rookies of the Year, and 56 all-region awardees.  Four players have been selected in the Major League Baseball draft under Twardoski.

Twardoski joined the Emory staff prior to the 1999 season as an assistant coach. After that season, he took over as head coach.

Twardoski played pro ball for 10 years in the Cleveland Indians, Boston Red Sox, New York Mets and Atlanta Braves organizations. He was the team MVP for Boston's Triple A affiliate, Pawtucket Red Sox, in 1990 and 1992. In Pawtucket, Twardoski shared playing time at first base and designated hitter with Mo Vaughn. Four times, Twardoski was singled out as the best first baseman in his league by "Baseball America" in its annual rankings. Twardoski was a 29th round pick by the Indians in 1986.

He is a 1986 graduate of the University of Alabama where he led the Southeastern Conference (SEC) with a .399 average his senior year. In the last game of his college career Twardoski went 3-for-3 against Kevin Brown, then pitching for Georgia Tech, who became a 200-game winner in the majors with six teams, most recently the New York Yankees.

After his playing career ended in 1995, Twardoski created and operated the East Coast Baseball Academy.

Twardoski and his wife, Tina, have one daughter, Chelsea, and one son, Trace.